New Insights into the Opioid Analgesic Profile of <i>cis</i>-(−)-<i>N</i>-Normetazocine-derived Ligands

In this work, we report on the in vitro and in vivo pharmacological properties of LP1 analogs to complete the series of structural modifications aimed to generate compounds with improved analgesia. To do that, the phenyl ring in the <i>N</i>-substituent of our lead compound LP1 was replaced by an el...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Giuliana Costanzo, Rita Turnaturi, Carmela Parenti, Salvatore Spoto, Silvia Piana, Maria Dichiara, Chiara Zagni, Anna Rita Galambos, Nariman Essmat, Agostino Marrazzo, Emanuele Amata, Mahmoud Al-Khrasani, Lorella Pasquinucci
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	MDPI AG 2023-06-01
سلاسل:	Molecules
الموضوعات:	μ opioid receptor competition binding assay mouse vas deferens assay tail-flick test CFA test
الوصول للمادة أونلاين:	https://www.mdpi.com/1420-3049/28/12/4827
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!