Glucose metabolism drives the hierarchical propagation of gray matter atrophy from the orbitofrontal cortex in obesity

Aims: To characterize the directional influence among brain regions across a metabolic gradient in obesity, thereby offering insights into the neurobiological pathways linking obesity to Type 2 Diabetes Mellitus (T2DM). Materials and methods: The study included 85 individuals with obesity and 89 hea...

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Détails bibliographiques

Auteurs principaux:	Weihua Li, Zhirong Miao, Chifa Ma, Yulong Jia, Chenfei Li, Yu Wang, Fengxia Yu, Demin Kong, Wei Zhu, Xiaoqing Yuan, Guowei Wu, Jiani Wang, Yiling Wang, Zhongxin Hong, Zhenchang Wang, Mingxia Yuan, Peng Zhang
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2026-04-01
Collection:	Brain Research Bulletin
Sujets:	Obesity Type 2 diabetes mellitus MRI Causal structural covariance network
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S0361923026000778
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