Glucose metabolism drives the hierarchical propagation of gray matter atrophy from the orbitofrontal cortex in obesity

Aims: To characterize the directional influence among brain regions across a metabolic gradient in obesity, thereby offering insights into the neurobiological pathways linking obesity to Type 2 Diabetes Mellitus (T2DM). Materials and methods: The study included 85 individuals with obesity and 89 hea...

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Detalhes bibliográficos

Principais autores:	Weihua Li, Zhirong Miao, Chifa Ma, Yulong Jia, Chenfei Li, Yu Wang, Fengxia Yu, Demin Kong, Wei Zhu, Xiaoqing Yuan, Guowei Wu, Jiani Wang, Yiling Wang, Zhongxin Hong, Zhenchang Wang, Mingxia Yuan, Peng Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-04-01
Colecção:	Brain Research Bulletin
Assuntos:	Obesity Type 2 diabetes mellitus MRI Causal structural covariance network
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0361923026000778
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