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Completion of the AAV Structural Atlas: Serotype Capsid Structures Reveals Clade-Specific Features

The capsid structures of most Adeno-associated virus (AAV) serotypes, already assigned to an antigenic clade, have been previously determined. This study reports the remaining capsid structures of AAV7, AAV11, AAV12, and AAV13 determined by cryo-electron microscopy and three-dimensional image recons...

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Principais autores: Mario Mietzsch, Ariana Jose, Paul Chipman, Nilakshee Bhattacharya, Nadia Daneshparvar, Robert McKenna, Mavis Agbandje-McKenna
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-01-01
Serier:Viruses
Fag:
AAV
serotype
capsid
cryo-EM
genome packaging
gene delivery
Online adgang:https://www.mdpi.com/1999-4915/13/1/101
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