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Characterization of the GBoV1 Capsid and Its Antibody Interactions

Human bocavirus 1 (HBoV1) has gained attention as a gene delivery vector with its ability to infect polarized human airway epithelia and 5.5 kb genome packaging capacity. Gorilla bocavirus 1 (GBoV1) VP3 shares 86% amino acid sequence identity with HBoV1 but has better transduction efficiency in seve...

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Autori principali: Jennifer Chun Yu, Mario Mietzsch, Amriti Singh, Alberto Jimenez Ybargollin, Shweta Kailasan, Paul Chipman, Nilakshee Bhattacharya, Julia Fakhiri, Dirk Grimm, Amit Kapoor, Indrė Kučinskaitė-Kodzė, Aurelija Žvirblienė, Maria Söderlund-Venermo, Robert McKenna, Mavis Agbandje-McKenna
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-02-01
Serie:Viruses
Soggetti:
bocavirus
capsid
parvovirus
cryo-EM
gene therapy
antigenicity
Accesso online:https://www.mdpi.com/1999-4915/13/2/330
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