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New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Mineralocorticoid-Receptor Blockers Exert Antihypertensive and Renoprotective Effects Independently of the Renin–Angiotensin System

The role of angiotensin II in mediating hypertension and renal diseases is well documented, and inhibition of the renin–angiotensin–aldosterone system elicits antihypertensive and renoprotective effects. There is increasing evidence implicating aldosterone, in addition to angiotensin II, in the path...

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Auteurs principaux: Akira Nishiyama, Koichi Hasegawa, Suwarni Diah, Hirofumi Hitomi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2010-01-01
Collection:Journal of Pharmacological Sciences
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S1347861319308977
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