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New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Characteristics and Usefulness of the Direct Renin Inhibitor Aliskiren

Since renin inhibition interferes with the first and rate-limiting steps in the renin–angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage. The newly developed direct renin inhibitor aliskiren has several attractive characteris...

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書誌詳細
主要な著者: Atsuhiro Ichihara, Mariyo Sakoda, Asako Kurauchi-Mito, Tatsuya Narita, Kenichiro Kinouchi, Kanako Bokuda, Hiroshi Itoh
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2010-01-01
シリーズ:Journal of Pharmacological Sciences
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S1347861319308953
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