Esculetin releases maturation arrest and induces terminal differentiation in leukemic blast cells by altering the Wnt signaling axes

Abstract Background The “Differentiation therapy” has been emerging as a promising and more effective strategy against acute leukemia relapses. Objective In extension to the revolutionising therapeutic outcomes of All Trans Retinoic Acid (ATRA) to induce terminal differentiation of Acute Promyelocyt...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ankit Mathur, Aman Gangwar, Daman Saluja
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-05-01
coleção:	BMC Cancer
Assuntos:	Acute Myeloid Leukemia (AML) Esculetin Blast cell differentiation Differentiation therapy Kasumi-1 Wnt signaling
Acesso em linha:	https://doi.org/10.1186/s12885-023-10818-1
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!