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Prostate Cancer-Specific Lysine 53 Acetylation of Cytochrome <i>c</i> Drives Metabolic Reprogramming and Protects from Apoptosis in Intact Cells

Cytochrome <i>c</i> (Cyt<i>c</i>) is important for both mitochondrial respiration and apoptosis, both of which are altered in cancer cells that switch to Warburg metabolism and manage to evade apoptosis. We earlier reported that lysine 53 (K53) of Cyt<i>c</i> is acetylated in prostate cancer. K53 is...

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Principais autores: Paul T. Morse, Junmei Wan, Tasnim Arroum, Mackenzie K. Herroon, Hasini A. Kalpage, Viktoriia Bazylianska, Icksoo Lee, Elisabeth I. Heath, Izabela Podgorski, Maik Hüttemann
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-06-01
Serier:Biomolecules
Fag:
cytochrome <i>c</i>
mitochondria
respiration
apoptosis
Warburg effect
prostate cancer
Online adgang:https://www.mdpi.com/2218-273X/14/6/695
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