Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements.
Predicting off-targets by computational methods is getting increasing importance in early drug discovery stages. We herewith present a computational method based on binding site three-dimensional comparisons, which prompted us to investigate the cross-reaction of protein kinase inhibitors with synap...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science (PLoS)
2010-08-01
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| Sarja: | PLoS ONE |
| Linkit: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012214&type=printable |
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