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Bax-inhibitor-1 knockdown phenotypes are suppressed by Buffy and exacerbate degeneration in a Drosophila model of Parkinson disease

Background Bax inhibitor-1 (BI-1) is an evolutionarily conserved cytoprotective transmembrane protein that acts as a suppressor of Bax-induced apoptosis by regulation of endoplasmic reticulum stress-induced cell death. We knocked down BI-1 in the sensitive dopa decarboxylase (Ddc) expressing neurons...

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Egile Nagusiak: P. Githure M’Angale, Brian E. Staveley
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: PeerJ Inc. 2017-02-01
Saila:PeerJ
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Sarrera elektronikoa:https://peerj.com/articles/2974.pdf
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