Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq

Triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy (NAC) represents a major clinical challenge; therefore, delineating tumor heterogeneity can provide novel insight into resistance mechanisms and potential therapeutic targets. Herein, we identified the transcriptional landsc...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Radhakrishnan Vishnubalaji, Nehad M. Alajez
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2021-12-01
Schriftenreihe:	Molecular Therapy: Oncolytics
Schlagworte:	triple-negative breast cancer TNBC neoadjuvant chemotherapy NAC resistance single cell
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2372770521001297
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