An optimised whole blood interleukin‐2 release assay is more sensitive than interferon‐γ ELISpot for detecting and quantifying gluten‐specific CD4+ T‐cell responses in coeliac disease
Abstract Objectives Detection of antigen‐specific T cells has been crucial for the study of autoimmune illnesses such as coeliac disease (CD). In CD, an oral gluten challenge is required to expand the rare population of circulating gluten‐specific T cells to detectable levels for IFN‐γ ELISpot detec...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2025-01-01
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| coleção: | Clinical & Translational Immunology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/cti2.70063 |
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