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Essential Role of mGBP7 for Survival of <named-content content-type="genus-species">Toxoplasma gondii</named-content> Infection

ABSTRACT Members of the murine guanylate-binding protein family (mGBP) are induced by interferon gamma (IFN-γ) and have been shown to be important factors in cell-autonomous immunity toward the intracellular pathogen Toxoplasma gondii. Previously, we identified that mGBP2 mediates disruption of the...

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Principais autores: Nora Steffens, Cornelia Beuter-Gunia, Elisabeth Kravets, Artur Reich, Larissa Legewie, Klaus Pfeffer, Daniel Degrandi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020-02-01
Serier:mBio
Fag:
guanylate-binding proteins
cell-autonomous immunity
Toxoplasma gondii
host-pathogen interaction
interferons
mGBP7
Online adgang:https://journals.asm.org/doi/10.1128/mBio.02993-19
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