Essential Role of mGBP7 for Survival of <named-content content-type="genus-species">Toxoplasma gondii</named-content> Infection

ABSTRACT Members of the murine guanylate-binding protein family (mGBP) are induced by interferon gamma (IFN-γ) and have been shown to be important factors in cell-autonomous immunity toward the intracellular pathogen Toxoplasma gondii. Previously, we identified that mGBP2 mediates disruption of the...

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Autori principali:	Nora Steffens, Cornelia Beuter-Gunia, Elisabeth Kravets, Artur Reich, Larissa Legewie, Klaus Pfeffer, Daniel Degrandi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2020-02-01
Serie:	mBio
Soggetti:	guanylate-binding proteins cell-autonomous immunity Toxoplasma gondii host-pathogen interaction interferons mGBP7
Accesso online:	https://journals.asm.org/doi/10.1128/mBio.02993-19
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