Selective pressure mediated by influenza virus M158–66 epitope-specific CD8+ T cells promotes accumulation of extra-epitopic amino acid substitutions associated with viral resistance to these T cells
Influenza viruses are notorious for their capacity to evade host immunity. Not only can they evade recognition by virus-neutralizing antibodies, there is also evidence that they accumulate mutations in epitopes recognized by virus-specific CD8+ T cells. In addition, we have shown previously that hum...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2024-05-01
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| Col·lecció: | Virus Research |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S0168170224000480 |
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