Review of the novel antifungal drug olorofim (F901318)

Abstract There is clearly a need for novel antifungal agents, not only concerning spectrum, but also oral bioavailability, tolerability, and drug-drug interactions. There is growing concern for antifungal resistance for current available antifungals, mainly driven by environmental fungicide use or l...

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主要な著者:	Yuri Vanbiervliet, Tine Van Nieuwenhuyse, Robina Aerts, Katrien Lagrou, Isabel Spriet, Johan Maertens
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-11-01
シリーズ:	BMC Infectious Diseases
主題:	Novel antifungal therapy Dihydroorotate dehydrogenase Olorofim F901318 Invasive fungal diseases Aspergillus
オンライン･アクセス:	https://doi.org/10.1186/s12879-024-10143-3
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