Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions
Abstract A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency of F3T3-fusion positivity, its associated genetic and methylation profiles, and...
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| Principais autores: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-11-01
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| coleção: | Acta Neuropathologica Communications |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s40478-020-01058-6 |
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