Glioblastoma, IDH-Wild Type With FGFR3-TACC3 Fusion: When Morphology May Reliably Predict the Molecular Profile of a Tumor. A Case Report and Literature Review

It has been reported that in-frame FGFR3-TACC3 fusions confer to glioblastomas, IDH-wild type (GBMs, IDHwt) some unusual morphologic features, including monomorphous rounded cells with ovoid nuclei, nuclear palisading, endocrinoid network of “chicken-wire” vessels, microcalcifications and desmoplast...

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Detalhes bibliográficos

Principais autores:	Giuseppe Broggi, Eliana Piombino, Roberto Altieri, Chiara Romano, Francesco Certo, Giuseppe Maria Vincenzo Barbagallo, Paolo Vigneri, Dario Condorelli, Lorenzo Colarossi, Cristina Colarossi, Gaetano Magro, Elena Tirrò
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-02-01
coleção:	Frontiers in Neurology
Assuntos:	FGFR3-TACC3 fusion glioblastoma unusual morphological features molecular biology diagnosis IDH-wildtype
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fneur.2022.823015/full
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