Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

ABSTRACT Tumor‐associated macrophages (TAMs) arise from monocytes and represent major contributors to the immunosuppressive microenvironment of solid tumors. However, the environmental cues that govern TAM differentiation and immunosuppressive activity remain incompletely understood. Here we demonst...

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Prif Awduron:	Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Wiley 2026-06-01
Cyfres:	Advanced Science
Pynciau:	ACLY extracellular vesicle hepatocellular carcinoma macrophage palmitoylation
Mynediad Ar-lein:	https://doi.org/10.1002/advs.202521458
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