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TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular vesicles.

Host-pathogen dynamics are constantly at play during enteroviral infection. Coxsackievirus B (CVB) is a common juvenile enterovirus that infects multiple organs and drives inflammatory diseases including acute pancreatitis and myocarditis. Much like other enteroviruses, CVB is capable of manipulatin...

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Bibliografische gegevens
Hoofdauteurs: Savannah Sawaged, Thomas Mota, Honit Piplani, Reetu Thakur, Deepti Lall, Elizabeth McCabe, Soojung Seo, Fayyaz S Sutterwala, Ralph Feuer, Roberta A Gottlieb, Jon Sin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2022-08-01
Reeks:PLoS Pathogens
Online toegang:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1010350&type=printable
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