TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular vesicles.

Host-pathogen dynamics are constantly at play during enteroviral infection. Coxsackievirus B (CVB) is a common juvenile enterovirus that infects multiple organs and drives inflammatory diseases including acute pancreatitis and myocarditis. Much like other enteroviruses, CVB is capable of manipulatin...

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Bibliografiske detaljer

Principais autores:	Savannah Sawaged, Thomas Mota, Honit Piplani, Reetu Thakur, Deepti Lall, Elizabeth McCabe, Soojung Seo, Fayyaz S Sutterwala, Ralph Feuer, Roberta A Gottlieb, Jon Sin
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2022-08-01
Serier:	PLoS Pathogens
Online adgang:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1010350&type=printable
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