TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis

Cytomegaloviruses all encode the viral inhibitor of caspase-8-induced apoptosis (vICA). After binding to this initiator caspase, vICA blocks caspase-8 proteolytic activity and ability to activate caspase-3 and/or caspase-7. In this manner, vICA has long been known to prevent apoptosis triggered via...

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Detalhes bibliográficos

Principais autores:	Pratyusha Mandal, A. Louise McCormick, Edward S. Mocarski
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-10-01
coleção:	Viruses
Assuntos:	apoptosis extrinsic apoptosis intrinsic apoptosis pyroptosis necroptosis inflammation
Acesso em linha:	https://www.mdpi.com/1999-4915/12/11/1221
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