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Trustworthy prediction of enzyme commission numbers using a hierarchical interpretable transformer

Abstract Accurate and trustworthy prediction of Enzyme Commission (EC) numbers is critical for understanding enzyme functions and their roles in biological processes. Despite the success of recently proposed deep learning-based models, there remain limitations, such as low performance in underrepres...

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Autori principali: Louis Dumontet, So-Ra Han, Jun Hyuck Lee, Tae-Jin Oh, Mingon Kang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-01-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-026-68727-3
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