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A bivalent glycopeptide to target two putative carbohydrate binding sites on FimH

FimH is a mannose-specific bacterial lectin found on type 1 fimbriae with a monovalent carbohydrate recognition domain (CRD) that is known from X-ray studies. However, binding studies with multivalent ligands have suggested an additional carbohydrate-binding site on this protein. In order to prove t...

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Principais autores: Thisbe K. Lindhorst, Kathrin Bruegge, Andreas Fuchs, Oliver Sperling
格式: Artigo
語言:Inglês
出版: Beilstein-Institut 2010-08-01
叢編:Beilstein Journal of Organic Chemistry
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在線閱讀:https://doi.org/10.3762/bjoc.6.90
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