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Deficiency of D‐alanyl‐D‐alanine ligase A attenuated cell division and greatly altered the proteome of Mycobacterium smegmatis

Abstract D‐Alanyl‐D‐alanine ligase A (DdlA) catalyses the dimerization of two D‐alanines yielding D‐alanyl‐D‐alanine required for mycobacterial peptidoglycan biosynthesis, and is a promising antimycobacterial drug target. To better understand the roles of DdlA in mycobacteria in vivo, we established...

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Auteurs principaux: Yingfei Chen, Yuefei Xu, Shufeng Yang, Sheng Li, Wenyong Ding, Wenli Zhang
Format: Artigo
Langue:Inglês
Publié: Wiley 2019-09-01
Collection:MicrobiologyOpen
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Accès en ligne:https://doi.org/10.1002/mbo3.819
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