Deficiency of D‐alanyl‐D‐alanine ligase A attenuated cell division and greatly altered the proteome of Mycobacterium smegmatis

Abstract D‐Alanyl‐D‐alanine ligase A (DdlA) catalyses the dimerization of two D‐alanines yielding D‐alanyl‐D‐alanine required for mycobacterial peptidoglycan biosynthesis, and is a promising antimycobacterial drug target. To better understand the roles of DdlA in mycobacteria in vivo, we established...

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Bibliographic Details

Main Authors:	Yingfei Chen, Yuefei Xu, Shufeng Yang, Sheng Li, Wenyong Ding, Wenli Zhang
Format:	Artigo
Language:	Inglês
Published:	Wiley 2019-09-01
Series:	MicrobiologyOpen
Subjects:	cell division D‐alanyl‐D‐alanine ligase A (DdlA) DdlA deficiency Mycobacterium smegmatis proteome
Online Access:	https://doi.org/10.1002/mbo3.819
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