An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1

The Hedgehog signaling pathway is part of the ancient developmental-evolutionary animal toolkit. Frequently co-opted to pattern new structures, the pathway is conserved among eumetazoans yet flexible and pleiotropic in its effects. The Hedgehog receptor, Patched, is transcriptionally activated by He...

Descripció completa

Dades bibliogràfiques

Autors principals:	David S Lorberbaum, Andrea I Ramos, Kevin A Peterson, Brandon S Carpenter, David S Parker, Sandip De, Lauren E Hillers, Victoria M Blake, Yuichi Nishi, Matthew R McFarlane, Ason CY Chiang, Judith A Kassis, Benjamin L Allen, Andrew P McMahon, Scott Barolo
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2016-05-01
Col·lecció:	eLife
Matèries:	gene regulation evolution of development (evo-devo) Hedgehog signaling cis-regulatory elements transcriptional regulation development
Accés en línia:	https://elifesciences.org/articles/13550
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!