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Allylamines, Benzylamines, and Fungal Cell Permeability: A Review of Mechanistic Effects and Usefulness against Fungal Pathogens

Allylamines, naftifine and terbinafine, and the benzylamine, butenafine, are antifungal agents with activity on the fungal cell membrane. These synthetic compounds specifically inhibit squalene epoxidase, a key enzyme in fungal sterol biosynthesis. This results in a deficiency in ergosterol, a major...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dalal Hammoudi Halat, Samar Younes, Nisreen Mourad, Mohamad Rahal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2022-11-01
Cyfres:Membranes
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/2077-0375/12/12/1171
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!