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Allylamines, Benzylamines, and Fungal Cell Permeability: A Review of Mechanistic Effects and Usefulness against Fungal Pathogens

Allylamines, naftifine and terbinafine, and the benzylamine, butenafine, are antifungal agents with activity on the fungal cell membrane. These synthetic compounds specifically inhibit squalene epoxidase, a key enzyme in fungal sterol biosynthesis. This results in a deficiency in ergosterol, a major...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Dalal Hammoudi Halat, Samar Younes, Nisreen Mourad, Mohamad Rahal
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-11-01
Schriftenreihe:Membranes
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Online-Zugang:https://www.mdpi.com/2077-0375/12/12/1171
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