In-vitro and in-vivo assessment of nirmatrelvir penetration into CSF, central nervous system cells, tissues, and peripheral blood mononuclear cells

Abstract Three years after SARS-CoV-2 emerged as a global infectious threat, the virus has become endemic. The neurological complications such as depression, anxiety, and other CNS complications after COVID-19 disease are increasing. The brain, and CSF have been shown as viral reservoirs for SARS-Co...

Descripció completa

Dades bibliogràfiques

Autors principals:	Sean N. Avedissian, Johid R. Malik, Anthony T. Podany, Michael Neely, Nathaniel J. Rhodes, Kimberly K. Scarsi, Marc H. Scheetz, Michael J. Duryee, Ukamaka O. Modebelu, Timothy M. Mykris, Lee C. Winchester, Siddappa N. Byrareddy, Courtney V. Fletcher
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-05-01
Col·lecció:	Scientific Reports
Matèries:	Nirmatrelvir/ritonavir Blood–brain-barrier Central nervous system
Accés en línia:	https://doi.org/10.1038/s41598-024-60935-5
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!