Discovery of <i>N</i>-(6-Methoxypyridin-3-yl)quinoline-2-amine Derivatives for Imaging Aggregated α-Synuclein in Parkinson’s Disease with Positron Emission Tomography

The fibrillary aggregation of α-synuclein is a hallmark of Parkinson’s disease (PD) and a potential target for diagnostics and therapeutics. Although substantial effort has been devoted to the development of positron emission tomography (PET) probes for detecting α-synuclein aggregates, no clinicall...

全面介紹

書目詳細資料

Principais autores:	Haiyang Zhao, Tianyu Huang, Dhruva D. Dhavale, Jennifer Y. O’Shea, Zsofia Lengyel-Zhand, Dinahlee Saturnino Guarino, Jiwei Gu, Xuyi Yue, Ying-Hwey Nai, Hao Jiang, Marshall G. Lougee, Vinayak V. Pagar, Hee Jong Kim, Benjamin A. Garcia, E. James Petersson, Chester A. Mathis, Paul T. Kotzbauer, Joel S. Perlmutter, Robert H. Mach, Zhude Tu
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2025-07-01
叢編:	Cells
主題:	α-synuclein aggregates Parkinson’s disease radiolabeling PET imaging tracer development
在線閱讀:	https://www.mdpi.com/2073-4409/14/14/1108
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!