The role of cytochrome bc 1 inhibitors in future tuberculosis treatment regimens

Abstract Tuberculosis (TB) remains the foremost cause of death from infectious diseases globally, prompting ongoing efforts to improve treatment options. This includes developing compounds with novel modes of action and identifying optimal treatment regimens that allow for treatment shortening. One...

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Main Authors: Clara Aguilar-Pérez, Anne J. Lenaerts, Cristina Villellas, Jerome Guillemont, John Dallow, Hannah Painter, Nicole C. Ammerman, Anis Hassan, Guillaume Golovkine, Laure Brock, Sylvie Sordello, Aurélie Chauffour, Alexandra Aubry, Thi Cuc Mai, Sarah Wong, Taane G. Clark, Kiyean Nam, Jeongjun Kim, Jinho Choi, Marjolein Crabbe, Jorge Esquivias, Nacer Lounis, Bart Stoops, Katie Amssoms, Jose M. Bartolome-Nebreda, Veronica Gruppo, Gregory T. Robertson, Nicolas Veziris, Anna M. Upton, Eric L. Nuermberger, Vivian Cox, Lluis Ballell, Benny Baeten, Anil Koul, Alexander S. Pym, Richard J. Wall, Dirk A. Lamprecht
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2025-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-64427-6
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