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Effect of cAMP signaling on expression of glucocorticoid receptor, Bim and Bad in glucocorticoid-sensitive and resistant leukemic and multiple myeloma cells

Stimulation of cAMP signaling induces apoptosis in glucocorticoid-sensitive and resistant CEM leukemic and MM.1 multiple myeloma cell lines, and this effect is enhanced by dexamethasone in both glucocorticoid-sensitive cell types and in glucocorticoid-resistant CEM cells. Expression of the mRNA for...

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Váldodahkkit: Hongli eDong, Michael E. Carlton, Adam eLerner, Paul Mark Epstein
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2015-10-01
Ráidu:Frontiers in Pharmacology
Fáttát:
Liŋkkat:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00230/full
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