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Flavomycin restores colistin susceptibility in multidrug-resistant Gram-negative bacteria

ABSTRACT Polymyxin is used as a last resort antibiotics for infections caused by multi-drug resistant (MDR) Gram-negative bacteria and is often combined with other antibiotics to improve clinical effectiveness. However, the synergism of colistin and other antibiotics remains obscure. Here, we reveal...

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Principais autores: Ying Huang, Yan Zhu, Hui-Ying Yue, Yi-Yun Liu, Li-Min Deng, Luchao Lv, Chengzhen Wang, Jun Yang, Jian-Hua Liu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2024-06-01
coleção:mSystems
Assuntos:
Enterobacterales
flavomycin
colistin
MDR
synergistic mechanism
Acesso em linha:https://journals.asm.org/doi/10.1128/msystems.00109-24
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