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CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma

ABSTRACT Replication complexes (RCs), formed by positive-strand (+) RNA viruses through rearrangements of host endomembranes, protect their replicating RNA from host innate immune defenses. We have shown that two evolutionarily conserved defense systems, autophagy and interferon (IFN), target viral...

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Principais autores: Chaitanya Kurhade, Soowon Kang, Scott B. Biering, Seungmin Hwang, Glenn Randall
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2023-06-01
coleção:mBio
Assuntos:
autophagy
interferon gamma
replication compartments
Acesso em linha:https://journals.asm.org/doi/10.1128/mbio.00172-23
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