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Inhibition of type I interferon signaling is a conserved function of gamma-herpesvirus-encoded microRNAs

ABSTRACT Herpesviruses encode multiple factors that disarm innate immune signaling to evade host anti-viral responses. Several viral microRNAs expressed by Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) disrupt the induction of type I interferons (IFN) and/or the subsequ...

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Furkejuvvon:
Váldodahkkit: Devin N. Fachko, Yan Chen, Nikita S. Ivanov, Bonnie Goff, Brian Pendergrass, Darby G. Oldenburg, Ryan D. Estep, Scott W. Wong, Rebecca L. Skalsky
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology 2026-02-01
Ráidu:Journal of Virology
Fáttát:
JAK/STAT pathway
type I interferon
innate immunity
microRNAs
herpesvirus
Liŋkkat:https://journals.asm.org/doi/10.1128/jvi.01579-25
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