Chronic fluoxetine modulates perineuronal nets and inhibitory neuronal function in relation to behavioral outcomes

Chronic fluoxetine administration has been reported to enhance neural plasticity in the adult brain, but the underlying structural correlates remain incompletely understood. In particular, the impact of fluoxetine on aggrecan-positive perineuronal nets (PNNs)—critical regulators of plasticity—is lar...

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Main Authors: Hiroshi Ueno, Eriko Kitano, Sachiko Mori, Yu Takahashi, Shinji Murakami, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara
格式: Artigo
語言:Inglês
出版: Elsevier 2025-12-01
叢編:IBRO Neuroscience Reports
主題:
Fluoxetine
Neuroplasticity
Perineuronal nets
Aggrecan
Parvalbumin
Behavior
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2667242125001654
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