DNA clasping by mycobacterial HU: the C-terminal region of HupB mediates increased specificity of DNA binding.

BACKGROUND: HU a small, basic, histone like protein is a major component of the bacterial nucleoid. E. coli has two subunits of HU coded by hupA and hupB genes whereas Mycobacterium tuberculosis (Mtb) has only one subunit of HU coded by ORF Rv2986c (hupB gene). One noticeable feature regarding Mtb H...

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Hlavní autoři:	Sandeep Kumar, Abhijit A Sardesai, Debashree Basu, Kalappagowda Muniyappa, Seyed E Hasnain
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2010-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC2932737?pdf=render
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