The role of two major nucleoid-associated proteins in Streptomyces, HupA and HupS, in stress survival and gene expression regulation

Abstract Background Streptomyces are sporulating soil bacteria with enormous potential for secondary metabolites biosynthesis. Regulatory networks governing Streptomyces coelicolor differentiation and secondary metabolites production are complex and composed of numerous regulatory proteins ranging f...

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Hauptverfasser:	Agnieszka Strzałka, Jakub Mikołajczyk, Klaudia Kowalska, Michał Skurczyński, Neil A. Holmes, Dagmara Jakimowicz
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-10-01
Schriftenreihe:	Microbial Cell Factories
Schlagworte:	Streptomyces Nucleoid-associated proteins (NAPs) HU Gene expression regulation Stress response Secondary metabolite gene cluster
Online-Zugang:	https://doi.org/10.1186/s12934-024-02549-0
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