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Structure and transport mechanism of the human prostaglandin transporter SLCO2A1

Abstract SLCO2A1 is a member of the organic anion transporting polypeptide (OATP) family, which preferentially transports prostaglandins (PGs) into cells and plays a vital role in regulating PGs inactivation and distribution. Dysregulation or genetic mutation of SLCO2A1 is associated with primary hy...

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Detalhes bibliográficos
Main Authors: Zhanyi Xia, Guangyuan Lu, Di Wu, Jun Zhao, Bowen Zhang, Haoran Xu, Yingying Du, Daohua Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-08-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-025-63615-8
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