Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease
Abstract This study presents a novel approach for mapping global chromatin interactions using S1 nuclease, a sequence-agnostic enzyme. We develop and outline a protocol that leverages S1 nuclease's ability to effectively introduce breaks into both open and closed chromatin regions, allowing for comp...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2023-12-01
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| Schriftenreihe: | Epigenetics & Chromatin |
| Online-Zugang: | https://doi.org/10.1186/s13072-023-00524-4 |
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