Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease

Abstract This study presents a novel approach for mapping global chromatin interactions using S1 nuclease, a sequence-agnostic enzyme. We develop and outline a protocol that leverages S1 nuclease's ability to effectively introduce breaks into both open and closed chromatin regions, allowing for comp...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Gridina Maria, Popov Andrey, Shadskiy Artem, Torgunakov Nikita, Kechin Andrey, Khrapov Evgeny, Ryzhkova Oxana, Filipenko Maxim, Fishman Veniamin
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2023-12-01
Цуврал:	Epigenetics & Chromatin
Онлайн хандалт:	https://doi.org/10.1186/s13072-023-00524-4
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!