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Neuronal Menin Overexpression Rescues Learning and Memory Phenotype in CA1-Specific α7 nAChRs KD Mice

The perturbation of nicotinic cholinergic receptors is thought to underlie many neurodegenerative and neuropsychiatric disorders, such as Alzheimer’s and schizophrenia. We previously identified that the tumor suppressor gene, <i>MEN1</i>, regulates both the expression and synaptic targeting of α7 nA...

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Principais autores: Shadab Batool, Basma Akhter, Jawwad Zaidi, Frank Visser, Gavin Petrie, Matthew Hill, Naweed I. Syed
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2021-11-01
סדרה:Cells
נושאים:
learning and memory
nicotinic cholinergic receptors
menin
synaptogenesis
extracellular activity
brain connectivity
גישה מקוונת:https://www.mdpi.com/2073-4409/10/12/3286
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