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Dynamic CRM occupancy reflects a temporal map of developmental progression

Abstract Development is driven by tightly coordinated spatio‐temporal patterns of gene expression, which are initiated through the action of transcription factors (TFs) binding to cis‐regulatory modules (CRMs). Although many studies have investigated how spatial patterns arise, precise temporal cont...

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Principais autores: Bartek Wilczyński, Eileen E M Furlong
Format: Artigo
Sprog:Inglês
Udgivet: Springer Nature 2010-06-01
Serier:Molecular Systems Biology
Fag:
cis‐regulatory modules
developmental networks
dynamic binding
temporal regulation
transcription factor binding
Online adgang:https://doi.org/10.1038/msb.2010.35
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