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CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells

Abstract Circadian genes control most of the physiological functions in cancer cells, including cell proliferation, migration, and invasion. The CLOCK and BMAL1 complex plays a central role in circadian rhythms. Previous studies have shown that circadian genes may act as oncogenes or tumor-suppresso...

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Detaylı Bibliyografya
Asıl Yazarlar: Teng-jiao Ma, Zhi-wei Zhang, Yi-lu Lu, Ying-ying Zhang, Da-chang Tao, Yun-qiang Liu, Yong-xin Ma
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2018-10-01
Seri Bilgileri:Experimental and Molecular Medicine
Online Erişim:https://doi.org/10.1038/s12276-018-0156-4
Etiketler: Etiketle
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