The circadian clock gene BMAL1 modulates autoimmunity features in lupus

ObjectivesAn important pathogenic role for neutrophils in systemic lupus erythematosus (SLE) has been proposed. Neutrophils that lack brain and muscle aryl hydrocarbon receptor nuclear translocator-like 1 (Bmal1), one of the clock genes, are defective in aging and proinflammatory responses. We asses...

Descripción completa

Detalles Bibliográficos

Autores principales:	Shuichiro Nakabo, Donavon Sandoval-Heglund, Norio Hanata, Stephen Brooks, Victoria Hoffmann, Mingzeng Zhang, William Ambler, Zerai Manna, Elaine Poncio, Sarfaraz Hasni, Shamima Islam, Stefania Dell’Orso, Mariana J. Kaplan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-11-01
Colección:	Frontiers in Immunology
Materias:	systemic lupus erythematosus neutrophils autoantibody clock gene Bmal1 April
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1465185/full
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!