The circadian clock gene BMAL1 modulates autoimmunity features in lupus

ObjectivesAn important pathogenic role for neutrophils in systemic lupus erythematosus (SLE) has been proposed. Neutrophils that lack brain and muscle aryl hydrocarbon receptor nuclear translocator-like 1 (Bmal1), one of the clock genes, are defective in aging and proinflammatory responses. We asses...

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Hlavní autoři:	Shuichiro Nakabo, Donavon Sandoval-Heglund, Norio Hanata, Stephen Brooks, Victoria Hoffmann, Mingzeng Zhang, William Ambler, Zerai Manna, Elaine Poncio, Sarfaraz Hasni, Shamima Islam, Stefania Dell’Orso, Mariana J. Kaplan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-11-01
Edice:	Frontiers in Immunology
Témata:	systemic lupus erythematosus neutrophils autoantibody clock gene Bmal1 April
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1465185/full
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