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RIOK-1 Is a Suppressor of the p38 MAPK Innate Immune Pathway in Caenorhabditis elegans

Innate immunity is the primary defense mechanism against infection in metazoans. However, aberrant upregulation of innate immune-signaling pathways can also be detrimental to the host. The p38 MAPK/PMK-1 innate immune-signaling pathway has been demonstrated to play essential roles in cellular defens...

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Principais autores: Yi-Wei Chen, Wen-Chien Ko, Chang-Shi Chen, Po-Lin Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-04-01
Serier:Frontiers in Immunology
Fag:
riok-1
p38 MAPK/pmk-1
skn-1
innate immunity
immune suppressor
Aeromonas dhakensis
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00774/full
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