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RIOK-1 Is a Suppressor of the p38 MAPK Innate Immune Pathway in Caenorhabditis elegans

Innate immunity is the primary defense mechanism against infection in metazoans. However, aberrant upregulation of innate immune-signaling pathways can also be detrimental to the host. The p38 MAPK/PMK-1 innate immune-signaling pathway has been demonstrated to play essential roles in cellular defens...

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Hlavní autoři: Yi-Wei Chen, Wen-Chien Ko, Chang-Shi Chen, Po-Lin Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-04-01
Edice:Frontiers in Immunology
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On-line přístup:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00774/full
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