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Single-cell RNA-seq reveals a repair pattern in cystic lesions in steroid induced osteonecrosis of the femoral head

BackgroundStudies have indicated that cystic lesions play a crucial role in the repair processes of steroid-induced osteonecrosis of the femoral head and its subsequent collapse. Here, we employed single-cell RNA sequencing (scRNA-seq) technology to investigate the transcriptomic landscape and repai...

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Principais autores: Peng Peng, Jiaqing Tian, Kun Lin, Weihua Fang, Fangming Yao, Xiaoqiang Yang, Wenyuan Hou, Fangjun Xiao, Shun Lu, Wei He, Mincong He, Huan Xiao, Qiushi Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-09-01
coleção:Frontiers in Immunology
Assuntos:
steroid-induced osteonecrosis of the femoral head
single-cell RNA sequencing
chondrocyte
cystic lesions
osteogenic differentiation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1626337/full
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